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Jaap M Middeldorp Selected Research

Epstein-Barr virus encoded RNA 1

1/2017High Levels of EBV-Encoded RNA 1 (EBER1) Trigger Interferon and Inflammation-Related Genes in Keratinocytes Expressing HPV16 E6/E7.
2/2016Sensing of latent EBV infection through exosomal transfer of 5'pppRNA.
2/2004EBV-positive gastric adenocarcinomas: a distinct clinicopathologic entity with a low frequency of lymph node involvement.
8/2002A rapid and reliable enzyme immunoassay PCR-based screening method to identify EBV-carrying gastric carcinomas.

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Jaap M Middeldorp Research Topics

Disease

31Neoplasms (Cancer)
11/2021 - 05/2002
25Nasopharyngeal Carcinoma
01/2022 - 05/2002
9Epstein-Barr Virus Infections
01/2019 - 01/2003
9Carcinoma (Carcinomatosis)
03/2018 - 08/2002
6Infections
01/2019 - 02/2002
6Lymphoma (Lymphomas)
06/2011 - 07/2005
5Infectious Mononucleosis (Glandular Fever)
11/2018 - 10/2003
4Burkitt Lymphoma (Burkitt's Lymphoma)
01/2019 - 06/2009
4Hodgkin Disease (Hodgkin's Disease)
08/2016 - 05/2002
4Malaria
11/2015 - 06/2009
3Carcinogenesis
01/2017 - 12/2009
2Nasopharyngeal Neoplasms (Cancer of the Nasopharynx)
01/2017 - 04/2012
2Inflammation (Inflammations)
01/2017 - 02/2016
2Latent Infection
02/2016 - 02/2002
2Pathologic Complete Response
11/2006 - 01/2002
1Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
11/2021
1Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
11/2021
1B-Cell Lymphoma (Lymphoma, B Cell)
11/2021
1Head and Neck Neoplasms (Head and Neck Cancer)
01/2019
1Coinfection
01/2019
1Uterine Cervical Neoplasms (Cancer of the Cervix)
01/2017
1Falciparum Malaria (Plasmodium falciparum Malaria)
11/2015
1Tetanus
11/2015
1Necrosis
01/2015
1Lymphoproliferative Disorders (Lymphoproliferative Disorder)
12/2014
1Parkinson Disease (Parkinson's Disease)
07/2014
1Parasitemia
03/2012
1B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia)
02/2011
1Starvation
10/2010
1Multiple Sclerosis
09/2010
1Hypoxia (Hypoxemia)
12/2009
1Chronic Renal Insufficiency
10/2009

Drug/Important Bio-Agent (IBA)

18Proteins (Proteins, Gene)FDA Link
12/2019 - 11/2002
15DNA (Deoxyribonucleic Acid)IBA
01/2022 - 08/2002
11Immunoglobulin A (IgA)IBA
11/2019 - 07/2004
11AntibodiesIBA
11/2019 - 11/2002
9RNA (Ribonucleic Acid)IBA
01/2019 - 02/2002
9AntigensIBA
11/2015 - 05/2002
9Immunoglobulin G (IgG)IBA
11/2015 - 07/2004
5EBV-encoded nuclear antigen 1IBA
12/2019 - 05/2002
5MicroRNAs (MicroRNA)IBA
01/2019 - 04/2010
5Membrane Proteins (Integral Membrane Proteins)IBA
01/2014 - 05/2002
4Messenger RNA (mRNA)IBA
01/2017 - 07/2005
4Viral DNAIBA
01/2017 - 05/2011
4Epstein-Barr virus encoded RNA 1IBA
01/2017 - 08/2002
4EnzymesIBA
05/2009 - 08/2002
3VaccinesIBA
01/2019 - 10/2009
3Antiviral Agents (Antivirals)IBA
11/2018 - 02/2002
3Peptides (Polypeptides)IBA
08/2016 - 10/2010
2Biomarkers (Surrogate Marker)IBA
01/2022 - 04/2012
2Viral ProteinsIBA
12/2019 - 12/2017
2Histone Deacetylases (Histone Deacetylase)IBA
01/2016 - 12/2014
2Telomerase (Telomerase Reverse Transcriptase)IBA
01/2015 - 10/2010
2Biological ProductsIBA
10/2010 - 11/2002
2ImmunosorbentsIBA
05/2009 - 11/2002
2Nuclear Antigens (Extractable Nuclear Antigens)IBA
07/2004 - 01/2004
1Cell-Free Nucleic AcidsIBA
11/2021
1Edetic Acid (EDTA)FDA Link
11/2021
1Heparin (Liquaemin)FDA LinkGeneric
11/2021
1LithiumIBA
11/2021
1Tumor Biomarkers (Tumor Markers)IBA
01/2019
1Circulating MicroRNAIBA
01/2019
1DiarylheptanoidsIBA
03/2018
1fialuridineIBA
12/2017
1Viral RNAIBA
01/2017
1InterferonsIBA
01/2017
1Indicators and Reagents (Reagents)IBA
01/2017
1romidepsin (FK228)FDA Link
01/2016
1Histone Deacetylase InhibitorsIBA
01/2016
1Protein Isoforms (Isoforms)IBA
01/2016
1Epstein-Barr Virus Nuclear AntigensIBA
11/2015
1Tumor Necrosis Factor Receptor-Associated Peptides and ProteinsIBA
01/2015
1Proteasome InhibitorsIBA
12/2014
1Bortezomib (Velcade)FDA Link
12/2014
1SynucleinsIBA
07/2014
1NF-kappa B (NF-kB)IBA
10/2013
1Cyclin D1IBA
10/2013
1Small Interfering RNA (siRNA)IBA
10/2013
1VorinostatFDA Link
10/2012
1Ganciclovir (Cytovene)FDA LinkGeneric
09/2012
1GemcitabineFDA Link
09/2012
1Valproic Acid (Depakote)FDA LinkGeneric
09/2012
1Matrix Metalloproteinase 9 (Gelatinase B)IBA
02/2011
1Immunoglobulin M (IgM)IBA
10/2010
1Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
10/2010
1Transforming Growth Factor beta (TGF-beta)IBA
10/2010
1Merozoite Surface Protein 1 (MSA1)IBA
07/2010
1Hypoxia-Inducible Factor 1IBA
12/2009
1Oxygen (Dioxygen)IBA
12/2009
1Epstein-Barr virus EBV-associated membrane antigenIBA
12/2009
1Aluminum Hydroxide (Algeldrate)FDA Link
10/2009
1Glycoproteins (Glycoprotein)IBA
10/2009
1Cell ExtractsIBA
08/2008

Therapy/Procedure

5Therapeutics
12/2017 - 11/2006
2Radiotherapy
01/2014 - 11/2006
2Drug Therapy (Chemotherapy)
01/2014 - 11/2006
2Aftercare (After-Treatment)
04/2013 - 01/2002
1Chemoradiotherapy
01/2014
1Injections
10/2009
1Transplantation
10/2009